Endocrine Abstracts

Primary adrenal lymphoma is an extremely rare type of lymphoma. There have been only about 200 cases described in the literature so far. About a half of patients can present with adrenal insufficiency. We report a case of a 70- year-old previously fit and well patient referred to Endocrinology services after a CT scan of her adrenal showed bilateral adrenal masses right measuring 6 cm and left measuring 9 cm. CT was performed as she complained of 9 kilograms weight loss in las...

Background: Birth control is widely encouraged to prevent unwanted pregnancies and around two-third of women use contraception. Prescribed contraceptives may result in amenorrhoea or withdrawal bleeds which can mask the initial symptoms of many endocrine disorders delaying diagnosis and treatment.Case Summary: A 43-year old Filipino female nurse was referred for headache, uncontrolled hypertension, weight gain, hirsutism and acne with raised serum testos...

A previously fit and well 49-year-old gentleman presented to hospital with vomiting and myalgia. Three weeks previously he had been admitted with acute pancreatitis, but no cause was found. An incidental hypercalcaemia was also noted at that time. He had lost approximately two stone in weight in the previous three months and had become more short of breath on exertion. He had a strong family history for type I diabetes mellitus, but otherwise there was no significant history.<...

A 20-year-old gentleman with an established diagnosis of Chronic fatigue syndrome was admitted to hospital with palpitations and shortness of breath on exertion. He had been taking ‘healthy supplements’ for his ME for a year. On examination, he was noted to be tachycardic with a heart rate of 120–150 beats/minute. ECG confirmed sinus tachycardia. Further investigations revealed a free thyroxine (fT4) of 29.4 pmol/l and thyroid stimulating hormone (TSH...

A 21-year-old female patient was referred from the eye clinic after she was noted to have bilateral papilloedema during a routine eye examination. She gave a 3 months history of intermittent headaches and fleeting episodes of profuse sweating and rash, unrelated to the headaches. She had been investigated by the GP with routine blood tests which were found to be normal.On examination, she was noted to be tachycardic at 100 beats/min and hypertensive at 1...

Adrenal Leiomyomas are very rare tumours. 20 cases have been reported to date. Their management remains difficult and challenging. They tend to present with flank or abdominal pain and have very little biochemical activity, if any.Case presentation: We present a case of a young 44 year old female. She was referred to Endocrinology services with a history of 2 weeks abdominal pain. She underwent an ultrasound organised in primary care which was suspicious...

Various haematological abnormalities have been reported to be associated with treatment of hyperthyroidism. The Association between neutropenia and untreated hyperthyroidism has been described although the aetiology is unknown, but thought to be related to autoimmunity.Case: A 41 year old Nepalese lady presented with a three month history of poor sleep and loss of weight. She was found to be thyrotocxic with T4 of 64 mol/l (10–24), T...

We describe a case of 38 year old female of Indian origin who presented with symptoms of Graves disease to our clinic. She had a diffusely enlarged goitre and minimal eye signs. Her T4 was 62 pmol/L(9–24), T3 9 pmol/L(3.5–6.5), and TSH was <0.01 mu/L (0.3–5.0). Radioactive iodine uptake scan revealed the presence of increased uptake throughout the gland. She was treated with carbimazole for 18 months and is in remission at present.Abou...

We describe a case of parathyroid carcinoma which is a rare, yet important cause of primary hyperparathyroidism.A 22 year old soldier was referred by army medical officer because of abnormal blood test results. He gave a history of weight loss of about 10 kg, increasing shortness of breath and malaise for 1 month prior to presentation. His past medical history was unremarkable, he was a non smoker and did not drink alcohol. He was not on any regular trea...

Transient mild hyperthyroidism is fairly common in women with hyperemesis gravidarum, occurring in up to two-thirds of them. It is also a well known fact that pregnant women with severe hyperemesis gravidarum can progress to develop Wernicke’s encephalopathy. Hyperthyroidism, without any other risk factors, has been described to accelerate the process of thiamine depletion as well. This is much less recognised.We describe the case of a 32-year-old P...